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Research > Chapter 9060



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IL-3 combination IL-4, induces expression functional CD1 molecules monocytes.

IL-3 dendritic cell progress function. comparison GM-CSF IL-4.


IL-3 increases marrow peripheral erythroid precursors chronic pure red cell aplasia presenting childhood.


IL-3 increases surface proteoglycan synthesis haemopoietic progenitors adhesiveness heparin-binding domain fibronectin.


IL-3 induces differentiation bone marrow precursor cells osteoclast-like cells.





IL-3 important differentiation factor progress prostaglandin E2-producing macrophages C57BL/6 BALB/c mice.

IL-3 produced normal stroma long-term bone marrow cultures.

IL-3 promotes basophilic differentiation KU812 cells high affinity binding sites.

IL-3 promotes production IL-4 splenic non-B, non-T cells answer Fc receptor cross-linkage.

IL-3 receptor expression, regulation role cells vasculature.


IL-3 signaling function Src kinases, JAKs STATs. covert liaison unveiled.

IL-3 specifically inhibits GM-CSF binding higher affinity receptor.

IL-3 induced haemopoietic stem cell proliferation - proof G protein independent mitogenic signalling events.

IL-3 withdrawal activates CrmA-insensitive poly (ADP-ribose) polymerase cleavage enzyme factor-dependent myeloid progenitor cells.


IL-3, IL-5, granulocyte-macrophage colony-stimulating factor potentiate basophil mediator release induced eosinophil granule major basic protein.

IL-3, IL-5, granulocyte-macrophage colony-stimulating factor receptor alpha-subunit, usual beta-subunit expression peripheral leukocytes blood dendritic cells.

IL-3-Induced Histamine Release Human Basophils - Dissociation cationic dye binding down-regulation Na+ K+.

IL-3-LA production mononuclear cells patients multiple sclerosis - Influence cure intravenous immunoglobulins.


IL-3-dependent mast cells attach plate-bound vitronectin. Demonstration augmented proliferation answer signals transduced cell surface vitronectin receptors.

IL-3-dependent mast cells attach plate-bound vitronectin - Demonstration augmented proliferation answer signals transduced cell surface vitronectin receptors.

IL-3-dependent murine mast cells undergo apoptosis removal IL-3 - Prevention apoptosis c-kit ligand.

IL-3-dependent murine mast cells undergo apoptosis removal IL-3 - prevention apoptosis ckit ligand.

IL-3-induced activation protein kinases mast cell megakaryocyte R6-XE.4 line.

IL-3-induced coexpression histidine decarboxylase, IL-4 IL-6 mRNA murine basophil precursors.


IL-3-induced generation alkylacylglycerol diacylglycerol IL-3-dependent cell line.

IL-3-induced histamine release human basophils. Dissociation cationic dye binding down-regulation Na+ K+.

IL-3-mediated TNF production mast cell progress.

IL-3-mediated enhancement particulate antigen presentation macrophages.

IL-31 cutaneous lymphocyte antigen-positive skin homing T cells patients atopic dermatitis.


IL-31. link T cells pruritus atopic skin inflammation.



IL-32 cytokine potential function disease.

IL-32 target rheumatoid arthritis.



IL-33 promote survival, adhesion cytokine production human mast cells.


IL-33 inhibits osteoclast structure indirectly osteoblastic cells.



IL-33 reduces cardiac remodeling, inhibits myocardial apoptosis improves survival experimental myocardial infarction.


IL-33 Potent Inducer Adaptive Immunity Intestinal Nematodes.

IL-33 potent inducer adaptive immunity intestinal nematodes.

IL-33, interleukin-1-like cytokine signals IL-1 receptor-related protein ST2 induces T helper type 2-associated cytokines.

IL-33, IL-1-like cytokine ligand ST2 receptor, chromatin-associated nuclear factor vivo.

IL-35 cytokine therapeutic effects collagen-induced arthritis expansion regulatory T cells.

IL-35 cytokine therapeutic effects collagen-induced arthritis expansion regulatory T cells suppression Th17 cells.

IL-35 cytokine therapeutic effects collagen-induced arthritis expansion regulatory T cells suppression Th17 cells (vol 37, pg 3021, 2007).

IL-4 (book review).

IL-4 Acts Myoblast Recruitment Factor Mammalian Muscle Growth.












IL-4 Is Critical Determinant Generation Allergic Inflammation Initiated Constitutively Active Stat6.

IL-4 Plus CD40 Monoclonal Antibody Induces Human B Cells gamma Subclass-specific Isotype Switch - Switching gamma-1, gamma-3, gamma-4, Not gamma-2.






IL-4 Suppresses Dendritic Cell Response Type I Interferons.


IL-4 Treatment cantreatment established gastrointestinal nematode infections immunocompetent immunodeficient mice.





IL-4 activates latent DNA-binding factor binds shared IFN-c IL-4 answer element present germ-line c1 Ig promoter.

IL-4 activates latent DNA-binding factor binds shared IFN-gamma IL-4 answer element present germ-line gamma-1 Ig promoter.


IL-4 acts synergistically IL-1b promote lymphocyte adhesion microvascular endothelium induction vascular cell adhesion molecule-1.

IL-4 addition differentiation CD34 progenitors delays maturation dendritic cells promoting survival.




IL-4 -5 prime human mast cells diverse profiles IgE-dependent cytokine production.

IL-4 and CXCR4 upregulation in HIV-infected and uninfected individuals from Maharashtra-Mumbai.

IL-4 IFN (a c)exert regulatory effects progress cytolytic potential Th1 Th2 human T cell clones.

IL-4 IFN (alpha gamma) exert regulatory effects progress cytolytic potential Th1 Th2 human T cell clones.


IL-4 IFN-c synergistically increase total polymeric IgA receptor levels human intestinal epithelial cells. Role protein tyrosine kinases.



IL-4 IFN-gamma synergistically increase total polymeric IgA receptor levels human intestinal epithelial cells. Role protein tyrosine kinases.




IL-4 IL-10 gene allelic polymorphism potential mechanisms promoting virus chronic hepatitis.


IL-4 IL-10 inhibition IFN-gamma- TNF-alpha-dependent nitric oxide production bovine mononuclear phagocytes exposed Babesia bovis merozoites.


IL-4 IL-10 modulate autoimmune haemolytic anaemia NZB mice.

IL-4 IL-10 modulation CD40-mediated signaling monocyte IL-1b synthesis rescue apoptosis.

IL-4 IL-10 regulate CXCR4 expression functions basophils.

IL-4 IL-10 synergistically inhibit survival human blood monocytes supported GM-CSF.







IL-4 IL-13 downregulate rolling adhesion leukocytes IL-1 TNF-alpha-activated endothelial cells limiting interval E-selectin expression.

IL-4 IL-13 exhibit comparable abilities reduce pyrogen-induced expression procoagulant activity endothelial cells monocytes.

IL-4 IL-13 expression chronic sinusitis - Relationship cellular infiltrate influence topical corticosteroid cure.

IL-4 IL-13 form negative feedback circuit surfactant protein-D allergic airway answer.

IL-4 IL-13 overlapping distinct effects HIV production monocytes.




IL-4 IL-13 stimulate myofibroblastic phenotype human lung fibroblasts c-Jun NH2-terminal kinase-dependent pathway.



IL-4 IL-13 induction SOCS-3 negatively regulates TNF-alpha IFN-gamma stimulated human beta defensin (HBD)-3 expression keratinocytes.

IL-4 IL-13 mRNA real-time PCR quantification blood assess allergic answer.

IL-4 IL-13 modulate IL-10 release endotoxin-stimulated murine peritoneal mononuclear phagocytes.

IL-4 IL-13 negatively regulate TNF-alpha- IFN-gamma-induced beta-defensin expression STAT-6, suppressor cytokine signaling (SOCS)-1, SOCS-3.

IL-4 IL-13 production differentiated T helper type 2 cells IL-4 dependent.


IL-4 IL-13 regulate induction indoleamine 2,3-dioxygenase activity control Toxoplasma gondii replication human fibroblasts activated IFN-gamma.

IL-4 IL-13 regulation ICAM-1 expression eosinophil recruitment Onchocerca volvulus keratitis.




IL-4 IL-13 upregulate arginase I expression cAMP JAK/STAT6 pathways vascular smooth muscle cells.

IL-4 IL-13 upregulate ornithine decarboxylase expression PI3K MAP kinase pathways vascular smooth muscle cells.

IL-4 IL-13, IL-10, chemotactic factors human osteoblasts.


IL-4 IL-15 promote immature mast cell adhesion endothelial cells chemotaxis.

IL-4 IL-2 promote human T-cell proliferation symmetrical independent pathways.

IL-4 IL-2 selectively rescue Th cell subsets glucocorticoid-induced apoptosis.

IL-4 IL-5 mRNA protein bronchial biopsies patients atopic nonatopic asthma - Proof intrinsic asthma distinct immunopathologic entity.

IL-4 IL-5 mRNA expression stimulated sputum asthmatic subjects - Comparison bronchial wash.

IL-4 IL-5-secreting lymphocyte populations preferentially induced parasite-derived antigens human tissue invasive nematode infections.

IL-4 IL-6 production bone marrow-derived mast cells enhanced cure environmental pollutants.

IL-4 IgE-anti-IgE modulation 15(S)-hydroxyeicosatetraenoic acid release mononuclear phagocytes.



IL-4 TNF-alpha-mediated proliferation human megakaryocytic line M-07e regulated stimulated autocrine production GM-CSF.

IL-4 glucocorticoid up-regulate CXCR4 expression human CD4+ T lymphocytes enhance HIV-1 replication.

IL-4 anti-CD40 protect Fas-mediated B cell apoptosis stimulate B cell growth differentiation.

IL-4 granulocyte-macrophage colony-stimulating factor selectively increase HLA-DR HLA-DP antigens HLA-DQ antigens human monocytes.

IL-4 insulin-like growth factor-I inhibit decline Bcl-2 promote survival IL-3-deprived myeloid progenitors.

IL-4 interferon-gamma production children atopic disease.

IL-4 roads lupuslike autoimmunity.

IL-4 prostaglandin E2 inhibit hypomethylation 5 regulatory area IFN-gamma gene differentiation naive CD4+ T cells.

IL-4 antagonizes induction FccRIII (CD16) expression transforming growth factor-b human monocytes.

IL-4 key factor influencing progress allergen-specific Th2-like cells atopic individuals.

IL-4 attenuates neuroinflammation stimulated amyloid-beta vivo vitro.


IL-4 attenuates transcriptional activation IFN-a- IFN-c-induced cellular gene expression monocytes monocytic cell lines.

IL-4 attenuates transcriptional activation IFN-alpha- IFN-gamma-induced cellular gene expression monocytes monocytic cell lines.

IL-4 augments anisomycin-induced p38 activation Akt pathway follicular dendritic cell (FDC)-like line.

IL-4 blocks up-regulation IL-2 receptors stimulated IL-2 normal human B cells.

IL-4 bypasses innate immune signals inhalational priming.

IL-4 correct defective IgE production SJA/9 mice.


IL-4 controls selective endothelium-driven transmigration eosinophils allergic individuals.

IL-4 decreases FccR membrane expression FccR-mediated cytotoxic activity human monocytes.


IL-4 insufficiency prevents eosinophilic rejection uncovers function neutrophils rejection MHC class II disparate skin grafts.



IL-4 depletion enhances host resistance passive IgA protection tuberculosis infection BALB/c mice.


IL-4 differentially regulates eotaxin MCP-4 lung epithelium circulating mononuclear cells.


IL-4 modulates role model human intestinal epithelium.

IL-4 directs progress Th2-like helper effectors.



IL-4 down-regulates responsiveness human intraepithelial lymphocytes.

IL-4 enhances IEC-6 intestinal epithelial cell proliferation influence IL-6 secretion.


IL-4 enhances IL-3 IL-8 gene expression human leukemic mast cell line.

IL-4 enhances hypoxia stimulated HIF-1 alpha protein levels human transformed intestinal cells.



IL-4 enhances programmed cell death (apoptosis) induced human monocytes.




IL-4 expression constitutive activation erk signaling vivo follicular lymphoma.

IL-4 expression onset islet inflammation predicts nondestructive insulitis nonobese diabetic mice.

IL-4 expression grafts transgenic mice fails prevent allograft rejection.

IL-4 expression neutrophils psoriasis lesional skin high-dose UVB exposure.


IL-4 expression human T cells selectively inhibited IL-1-alpha IL-1-beta.

IL-4 expression human T cells selectively inhibited IL-1a IL-1b.




IL-4 gene transcription human T cells suppressed T-bet.

IL-4 gene transfer bowel serosa leads intestinal inflammation smooth muscle hyperresponsiveness.


IL-4 schistosomiasis.


IL-4 vitro production upregulated Alzheimer's disease patients treated acetylcholinesterase inhibitors.

IL-4 increases GABAergic phenotype rat retinal cell cultures - Involvement muscarinic receptors protein kinase C.

IL-4 increases IL-2 production T cells answer accessory cell-independent stimuli.


IL-4 increases human endothelial cell adhesiveness T cells neutrophils.

IL-4 increases simian immunoinsufficiency virus replication enhanced SIV immune responses infested rhesus macaques.

IL-4 increases surfactant regulates metabolism vivo.

IL-4 stimulated CD23 (Fc epsilon RII) up-regulation equine peripheral blood mononuclear cells pulmonary alveolar macrophages.

IL-4 stimulated CD23 (FcepsilonRII) up-regulation equine peripheral blood monoculear cells pulmonary alveolar macrophages.

IL-4 stimulated CD23 (FcepsilonRII) up-regulation equine peripheral blood mononuclear cells pulmonary alveolar macrophages.

IL-4 stimulated leucocyte trafficking cynomolgus monkeys - Correlation expression adhesion molecules chemokine generation.

IL-4 stimulated neutrophilic maturation HL-60 cells activation human peripheral blood neutrophils.

IL-4 induces Fas resistance B cells.

IL-4 induces ICAM-1 expression human bronchial epithelial cells potentiates TNF-a.

IL-4 induces ICAM-1 expression human bronchial epithelial cells potentiates TNF-alpha.

IL-4 induces IL-13-independent allergic airway inflammation.

IL-4 induces IL-2 receptor p75 b-chain gene expression IL-2-dependent proliferation mouse T lymphocytes.

IL-4 induces IL-6 signs allergic-type inflammation nasal airways nonallergic individuals.

IL-4 induces LFA-1 LFA-3 expression Burkitt's lymphoma cell lines - demand activation phorbol myristate acetate induction homotypic cell adhesions.

IL-4 induces Th2 answer Leishmania major-infected mice.

IL-4 induces wide-spectrum intracellular signaling cascade CD8(+) T cells.

IL-4 induces adherence human eosinophils basophils neutrophils endothelium. Association expression VCAM-1.

IL-4 induces allergic-like inflammatory disease alters T cell progress transgenic mice.


IL-4 induces apoptosis endothelial cells caspase-3-dependent pathway.

IL-4 induces cAMP cGMP human monocytic cells.

IL-4 induces characteristic Th2 responses combined absence IL-5, IL-9, IL-13.

IL-4 induces chemotaxis blood eosinophils atopic dermatitis patients, normal individuals.

IL-4 induces conformational change CD20 antigen protein kinase C-independent pathway. Antagonistic influence anti-CD40 monoclonal antibody.


IL-4 induces eotaxin human dermal fibroblasts.

IL-4 induces eotaxin production corneal keratocytes epithelial cells.



IL-4 induces expression TARC/CCL17 uia STAT6 binding sites.

IL-4 induces germ-line IgE heavy chain gene transcription human fetal Pre-B cells - Proof differential expression functional IL-4 IL-13 receptors B cell ontogeny.

IL-4 induces germ-line IgE heavy chain gene transcription human fetal pre-B cells. Proof differential expression functional IL-4 IL-13 receptors B cell ontogeny.

IL-4 induces human B cell maturation IgE synthesis SCID-hu mice. Inhibition ongoing IgE production vivo cure IL-4/IL-13 receptor antagonist.

IL-4 induces human B cell maturation IgE synthesis SCID-hu mice - Inhibition ongoing IgE production vivo cure IL-4/IL-13 receptor antagonist.

IL-4 induces vivo production IFN-gamma NK NKT cells.

IL-4 induces lipogenesis porcine vascular endothelial cells, critical induction protection injury human complement.


IL-4 induces production lung collectin surfactant protein-D.

IL-4 induces serine phosphorylation STAT6 transactivation domain B lymphocytes.

IL-4 induces intracellular expression alpha chain high-affinity receptor IgE in vitro-generated dendritic cells.


IL-4 induces special rearrangment gamma 1 genes expressed unexpressed chromosomes lipopolysaccharide activated normal murine B cells.

IL-4 inducibility NKT cells, naive CD4(+) T cells TCR-gamma delta T cells.

IL-4 induction IgE class switching lipopolysaccharide-activated murine B cells occurs predominantly sequential switching.

IL-4 induction VCAM-1 endothelial cells involves activation protein tyrosine kinase.

IL-4 influences IL-2 production granulomatous inflammation murine schistosomiasis mansoni.


IL-4 influences differentiation vulnerability activation-induced cell death human naive CD8(+) T cells.

IL-4 inhibits H2O2 production antileishmanial capacity human cultured monocytes mediated IFN- gamma.

IL-4 inhibits H2O2 production antileishmanial capacity human cultured monocytes mediated IFN-c.

IL-4 inhibits IL-2 induction LAK cytotoxicity lymphocytes cultivar lymphoid tissues.

IL-4 inhibits IL-2 receptor expression IL-2-dependent proliferation human T cells.

IL-4 inhibits IL-2 synthesis IL-2-induced up-regulation IL-2Ra IL-2Rb chain CD4+ human T cells.

IL-4 inhibits IL-2-induced tumoricidal activity secretory functions human monocytes. Modulation IL-2 binding IL-2 receptor bc chain expression.

IL-4 inhibits IL-2-induced tumoricidal activity secretory functions human monocytes - Modulation IL-2 binding IL-2 receptor beta-gamma chain expression.

IL-4 inhibits P-glycoprotein normal malignant NK cells.

IL-4 inhibits apoptosis prevents mitochondrial damage inducing switch necrosis observed caspase inhibitors.

IL-4 inhibits binding cytotoxicity NK cells vascular endothelium.




IL-4 inhibits cell cycle progression human umbilical vein endothelial cells affecting p53, p21Waf1, cyclin D1, cyclin E expression.

IL-4 inhibits expression formyl peptide receptor gene mouse peritoneal macrophages.

IL-4 inhibits growth factor-stimulated rheumatoid synoviocyte proliferation blocking early phases cell cycle.

IL-4 inhibits human CD8 T cell expression usual IL-2 receptor gamma chain.

IL-4 inhibits macrophage-mediated killing Plasmodium falciparum vitro - potential parasite-immune evasion mechanism.

IL-4 inhibits macrophage-mediated killing Plasmodium falciparum vitro. potential parasite-immune evasion mechanism.




IL-4 inhibits proliferation renal carcinoma cells increasing expression p21WAF1 IRF-1.

IL-4 inhibits superoxide production human mononuclear phagocytes.

IL-4 inhibits LPS-induced expression CD14 monocyte-specific esterase mRNA MONO-MAC-6 cells.


IL-4 inhibits costimulatory activity IL-2 picolinic acid lipopolysaccharide IFN-c-treated macrophages.

IL-4 inhibits expression IL-8 induced human monocytes.

IL-4 inhibits expression high affinity IL-2 receptors monoclonal human B cells.


IL-4 inhibits migration human Langerhans cells downregulation TNF receptor II expression.


IL-4 inhibits synthesis IFN-c induces synthesis IgE human mixed lymphocyte cultures.

IL-4 inhibits vasoactive intestinal peptide production macrophages.

IL-4 instructs THI responses resistance Leishmania major vulnerable BALB/c mice.

IL-4 critical determinant generation allergic inflammation initiated constitutively active Stat6.

IL-4 differentiation factor transforming growth factor-beta secreting Th3 cells oral administration IL-4 enhances oral tolerance experimental allergic encephalomyelitis.



IL-4 reverse CD2-mediated negative apoptotic signal CD4-CD8-alpha-beta and/or gamma-delta T lymphocytes.


IL-4 essential systemic transfer delayed hypersensitivity T cell lines - Role gamma/delta cells.

IL-4 essential systemic transfer delayed hypersensitivity T cell lines - function c/d cells.

IL-4 effective IL-13 vitro differentiation dendritic cells peripheral blood mononuclear cells.


IL-4 protective progress toxoplasmic encephalitis.

IL-4 required defense mycobacterial infection.

IL-4 required IgE IgG1 increase IgG1 autoantibody structure mice treated mercuric chloride.


IL-4 key regulator herpes simplex virus-based gene therapy BALB/c experimental autoimmune encephalomyelitis.

IL-4 mRNA expression peritoneal cells episodes peritonitis patients continuous ambulatory peritoneal dialysis.

IL-4 mRNA transcription stimulated mouse bone marrow-derived mast cells MHC class II-dependent signaling pathway.

IL-4 unlock asthma allergic diseases.

IL-4 mediated conditioning human dendritic cell precursors IL-12p70 producing DC1 cells.

IL-4 mediates human B cell responsiveness schistosomal antigens.

IL-4 modulates histamine content mast cells mast cell/fibroblast co-culture Stat6 signaling pathway fibroblasts.

IL-4 modulates tissue factor expression human B lymphocytes answer phorbol myristate acetate.

IL-4 modulates transcriptional control mannose receptor mouse FSDC dendritic cells.


IL-4 neutralization TNF-a cure ameliorate disease intracellular pathogen IFN-c receptor-lacking mice.


IL-4 plays dominant function differential progress Tho Th1 Th2 cells.

IL-4 CD40 monoclonal antibody induces human B cell subclass-specific isotype switch - switching c1, c3, c4, c2.


IL-4 potentiates IL-2-dependent proliferation mouse cytotoxic T cells.



IL-4 prevents insulitis insulin-dependent diabetes mellitus nonobese diabetic mice potentiation regulatory T helper-2 cell role.


IL-4 primes human endothelial cells secondary responses histamine.

IL-4 producing CD4+ TCR-alpha-beta-int liver lymphocytes - Effect thymus, beta-2-microglobulin NK1.1 expression.


IL-4 production T cells naive donors. IL-2 required IL-4 production.

IL-4 production T depleted cells Nippostrongylus brasiliensis infested mice.

IL-4 production allergen-stimulated primary cultures - Identification basophils major IL-4-producing cell type.

IL-4 production human basophils lung segmental allergen challenge.

IL-4 production human polymorphonuclear neutrophils.

IL-4 production mediastinal lymph node cells mice intratracheally instilled diesel exhaust particulates antigen.

IL-4 production increased cigarette smokers.



IL-4 promotes anti-Ig-mediated protein kinase C translocation reverses phorbol ester-mediated protein kinase C down-regulation murine B cells.

IL-4 promotes macrophage progress rapidly stimulating lineage restriction bipotent granulocyte-macrophage colony-forming cells.

IL-4 promotes structure multinucleated giant cells macrophage precursors STAT6-dependent, homotypic mechanism - contribution E-cadherin.




IL-4 protects TNF- alpha -mediated cachexia death acute schistosomiasis.

IL-4 protects TNF-a-mediated cachexia death acute schistosomiasis.

IL-4 protects cells apoptosis insulin receptor substrate pathway independent signaling pathway.

IL-4 protects B-cell lymphoma cell line CH31 anti-IgM-induced growth arrest apoptosis - contribution PI-3 kinase/AKT pathway.


IL-4 rapidly produced V-beta-4 V-alpha-8 CD4+ T cells instructs Th2 progress vulnerability Leishmania major BALB/c mice.

IL-4 receptor alpha chain genetic polymorphism total IgE levels English population - Two-locus haplotypes informative individual SNPs.

IL-4 receptor alpha important modulator IL-4 IL-13 receptor binding - Implications progress therapeutic targets.


IL-4 receptor expression SAC-activated B-lymphocytes - Its function B-cell proliferation influence cyclosporine (CsA), prednisolone verapamil.




IL-4 receptor signal transduction human monocytes protein kinase C translocation.


IL-4 receptor signaling required mannose receptor expression macrophages recruited granulomata resident cells mice infested Schistosoma mansoni.

IL-4 receptors human medulloblastoma tumours serve sensitive target circular permuted IL-4-Pseudomonas exotoxin fusion protein.

IL-4 reciprocally regulates IL-1 IL-1 receptor antagonist expression human monocytes.


IL-4 regulates COX-2 PGE2production human non-small cell lung cancer.

IL-4 regulates IL-12 p40 expression post-transcriptionally promoter-based mechanism.



IL-4 regulates c-kit proto-oncogene product expression human mast myeloid progenitor cells.


IL-4 regulates endothelial cell activation IL-1, tumor necrosis factor, IFN-c.

IL-4 regulates endothelial cell activation IL-1, tumor necrosis factor, IFN-g.

IL-4 regulates morphology, cytoskeleton, proliferation human umbilical vein endothelial cells - Relationship vimentin CD23.

IL-4 regulation IL-6 production involves Rac/Cdc42- p38 MAPK-dependent pathways keratinocytes.

IL-4 regulation p38 MAPK signalling dependent cell type.

IL-4 regulation perforin gene expression BLT-esterase production alpha-CD3-induced activated killer cells.

IL-4 release human leukemic activated normal basophils.

IL-4 renders mast cells functionally responsive endothelin-1.

IL-4 demands generation secondary vivo IgE responses.

IL-4 responsive CD4+ T cells special myelin basic protein - IL-2 confers extended postactivation refractory phase.

IL-4 restores impaired contact hypersensitivity answer obese mice.

IL-4 restores impaired contact hypersensitivity answer obese mice fed high-fat diet enriched oleic acid.

IL-4 secreted individual naive CD4+ T cells acts autocrine manner stimulate Th2 differentiation.

IL-4 secretion histamine release human basophils differentially regulated protein kinase C activation.

IL-4 secretion CD4+NK1+ T cells induces monocyte chemoattractant protein-1 early listeriosis.

IL-4 selectively enhances FcgammaRIII expression signaling mouse mast cells.


IL-4 signaling regulated recruitment phosphatases, kinases, SOCS proteins receptor complex.

IL-4 signaling, gene transcription regulation, control effector T cells.

IL-4 stimulates expression CXCL-8, E-selectin, VEGF, inducible nitric oxide synthase mRNA equine pulmonary artery endothelial cells.

IL-4 stimulates growth chronic myelomonocytic leukemia cells (CMMoL) leukemic transformation occurred.

IL-4 supports generation dendritic cell subset murine bone marrow altered endocytosis capacity.

IL-4 suppresses UVB-induced apoptosis skin.

IL-4 suppresses cytokine gene expression stimulated IFN-c and/or IL-2 murine peritoneal macrophages.

IL-4 suppresses dendritic cell answer type I interferons.



IL-4 suppresses recovery cutaneous permeability barrier functions vivo.



IL-4 synergizes IL-10 anti-CD40 MoAbs stimulate B-cell differentiation patients usual variable immunoinsufficiency.

IL-4 synthesis vivo primed keyhole limpet hemocyanin-specific CD4+ T cells. Effect antigen concentration antigen-presenting cell type.

IL-4 synthesis vivo primed keyhole limpet hemocyanin-specific CD4-positive T cells - Effect antigen concentration antigen-presenting cell type.



IL-4 cure cure established gastrointestinal nematode infections immunocompetent immunodeficient mice.

IL-4 cure splenic B cells induces costimulatory molecules B7-1 B7-2.

IL-4 triggers autoimmune diabetes increasing self-antigen presentation pancreatic islets.

IL-4 up-regulates IL-1 receptor antagonist gene expression production human blood monocytes.


IL-4 upregulates FceRI alpha-chain messenger RNA eosinophils.

IL-4 upregulates FceRI-mediated TSLP expression human mast cells.

IL-4 upregulates IL-1-induced chemokine gene expression bone marrow stromal cells enhancing NF-kB activation.

IL-4 upregulates tenascin synthesis scleroderma healthy skin fibroblasts.

IL-4 utilizes alternative receptor drive apoptosis Th2 cells skews neonatal immunity Th2.

IL-4, IL-10 IFN-gamma distinct, interacting, effects differentiation-induced TNF-alpha TNF receptor releases cultured human monocytes.

IL-4, IL-10 IL-13 down-regulate monocyte-chemoattracting protein-1 (MCP-1) production activated intestinal epithelial cells.

IL-4, IL-10 IL-13 acute myelogenous leukemia.

IL-4, IL-10 IL-13 modulate Abeta(1-42)-induced cytokine chemokine production primary murine microglia human monocyte cell line.


IL-4, IL-13, dexamethasone augment fibroblast proliferation asthma.


IL-4, IL-5 IFN-gamma mRNA expression pulmonary lymphocytes equine heaves.

IL-4, IL-5 IL-10 required control M. bovis-BCG infection mice.

IL-4, IgE, interferon-gamma production pulmonary blastomycosis - Comparison mice untreated, immunized, treated antifungal (SCH 39304).

IL-4, IL-13, modulates TARC (thymus activation-regulated chemokine)/CCL17 IP-10 (interferon-induced protein 10 kDa)/CXCL10 release TNF-alpha IFN-gamma HaCaT cell line.

IL-4, tumor necrosis factor-a, increases endothelial cell adhesiveness lymphocytes activating cAMP-dependent pathway.

IL-4, tumor necrosis factor-alpha, increases endothelial cell adhesiveness lymphocytes activating cAMP-dependent pathway.

IL-4, vitamin D3, induces monoblastic cell line UG3 differentiate multinucleated giant cells osteoclast lineage.

IL-4, intron 3 variable number tandem repeats examination (VNTR), IL-13-1055 gene polymorphism patients asthma COPD Venezuela.


IL-4- IL-5-dependent protective immunity Onchocerca volvulus infective larvae BALB/cBYJ mice.

IL-4- IL-5-positive T lymphocytes, eosinophils, mast cells allergen-induced late-phase cutaneous reactions atopic subjects.

IL-4- IL-5-secreting lymphocyte populations preferentially induced parasite-derived antigens human tissue invasive nematode infections.

IL-4- IL-6-producing cells human periodontal disease tissue.

IL-4-588C > T polymorphism IL-4 receptor alpha Ex5+14A > G; Ex11+828A > G haplotype concur selecting H-pylori cagA subtype infections.

IL-4-588C > T polymorphism IL-4 receptor alpha haplotype concur selecting H-pylori cagA subtype infections.

IL-4-Based helper activity CD4+ T cells radiation sensitive.








IL-4-STAT6 Signal Transduction-Dependent Induction Clinical Phase Sjogren's Syndrome-Like Disease Nonobese Diabetic Mouse.

IL-4-STAT6 signal transduction-dependent induction medical phase Sjogrens Syndrome-like disease nonobese diabetic mouse.



IL-4-and IL-5-dependent protective immunity Onchocerca volvulus infective larvae BALB/cBYJ mice.


IL-4-lacking mice develop acute chronic relapsing collagen-induced arthritis.

IL-4-dependent CD86 expression requires JAK/STAT6 activation negatively regulated PKCdelta.

IL-4-dependent IgE class switching anti-trinitrophenyl B-cell hybridoma engagement antigen receptors.

IL-4-dependent IgE switch membrane IgA-positive human B cells.


IL-4-dependent effector phase autoimmune exocrinopathy defined NOD.IL-4-gene knockout mouse model Sjogren's syndrome.

IL-4-dependent induction Bcl-2 Bcl-XL activated T lymphocytes Stat6- PI 3-kinase-independent pathway.

IL-4-dependent proliferation BA/F3 cells expression growth-negative mutant human IL-4 receptor restored enforced expression Bcl-2.


IL-4-dependent up-regulation IL-4 receptor expression murine T B cells.

IL-4-expressing bronchoalveolar T cells asthmatic healthy subjects preferentially express CCR3 CCR4.


IL-4-independent pathways exacerbate methacholine-induced airway hyperreactivity mycoplasma respiratory disease.

IL-4-independent regulation vivo IL-9 expression.

IL-4-induced AID expression relevance IgA class switch recombination.

IL-4-induced B cell migration involves transient interactions beta-1 integrins extracellular matrix components.

IL-4-induced STAT6 suppresses IFN-c-stimulated STAT1-dependent transcription mouse macrophages.

IL-4-induced Stat6 activities affect apoptosis gene expression breast cancer cells.

IL-4-induced apoptosis peripheral blood eosinophils.


IL-4-induced cell proliferation production extracellular matrix proteins human conjunctival fibroblasts.


IL-4-induced expression IL-1 receptor antagonist gene mediated STAT6.


IL-4-induced macrophage-derived IGF-I protects myofibroblasts apoptosis growth factor withdrawal.

IL-4-induced migration eosinophils allergic inflammation.

IL-4-induced oxidative stress upregulates VCAM-1 gene expression human endothelial cells.

IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kappa B trans activation in nervous scheme (CNS) glial cells protects oligodendrocyte progenitors neuroinflammatory disease conditions - Implication CNS-demyelinating diseases.


IL-4-induced upregulation adenine nucleotide translocase 3 function Th cell survival apoptosis.

IL-4-mediated progress TGF-beta1-producing cells naive CD4+ T cells STAT6-independent mechanism.

IL-4-mediated drug resistance colon cancer stem cells.



IL-4-producing CD8(+) T cells immunological hallmark chronic GVHD.

IL-4-producing CD8+ T cell clones provide B cell.


IL-4-producing NK T cells biased IFN-gamma production IL-1Effect microenvironment functional capacities NK T cells.



IL-4-regulated enteropathy intestinal nematode infection.

IL-4-responsive human helper T cell clones tolerant growth inhibition tumor necrosis factor-a.

IL-4-secreting CD4+ T cells crucial progress CD8+ T-cell responses malaria liver stages.

IL-4-secreting NKT cells prevent hypersensitivity pneumonitis suppressing IFN-gamma-producing neutrophils.

IL-4-stimulated NF-kappa B activity required Stat6 DNA binding.




IL-4/IL-13 pathway genetics strongly effect serum IgE levels childhood asthma.

IL-4/IL-13 signaling JAK/STAT.

IL-4/Stat6 activities correlate apoptosis metastasis colon cancer cells.

IL-4R alpha gamma chain expression LPS- IL-4-stimulated MONO-MAC-6 cells.


IL-4R alpha polymorphism regulation IL-4 synthesis T cells - implication vulnerability subset murine lupus.

IL-4R alpha signaling important CD8(+) T cell cytotoxicity absence CD4(+) T cell.


IL-4R signaling required stimulate IL-10 establishment T(h)2 dominance.

IL-4RA IL-13 polymorphisms cytokine synthesis children alternaria sensitive moderate-severe asthma.

IL-4RA gene transfer recombinant retroviral vector prevents progress experimental asthma.

IL-4Ra Expression Bone Marrow-Derived Cells Is Necessary Sufficient Host Protection Acute Schistosomiasis.

IL-4Ra, IL-13 IL-10 polymorphisms allergic bronchopulmonary aspergillosis.

IL-5 Enhances vitro vivo Antigen-Specific IgA Production MHC Genetically Determined Low IL-5 Responder Mice.


IL-5 T-cell responses house dust mite progress allergen-specific IgE responses asthma preliminary 5 years life.

IL-5 accounts mouse pleural eosinophil accumulation triggered antigen LPS.

IL-5 activates 45-kilodalton mitogen-activated protein (MAP) kinase Jak-2 tyrosine kinase human eosinophils.


IL-5 IFN-gamma levels spirometric parameters stimulated sputum patients asma, allergic rhinitis controls.






IL-5 eosinophils mediate rejection fully histoincompatible vascularized cardiac allografts - Regulatory function alloreactive CD8+ T lymphocytes IFN-gamma.


IL-5 receptor - Which function play immune response?

IL-5 similar eosinophilopoietic cytokines - receptors function eosinophil-mediated inflammatory reactions.

IL-5 FIP1L1/PDGFRA fusion gene cooperatively promote eosinophil development, activation, signal transduction.

IL-5 thromboxane A2 receptor gene polymorphisms decreased pulmonary role Korean children atopic asthma.

IL-5 strong secretagogue human eosinophils.

IL-5 interferon-gamma (IFN-gamma) inhibits eosinophil apoptosis up-regulation bcl-2 expression.

IL-5 contributes worm expulsion muscle hypercontractility primary T. spiralis infection.

IL-5 insufficiency abolishes aspects airway remodelling murine model lung inflammation.


IL-5 drives eosinophils bone marrow blood tissues guinea-pig model visceral larva migrans syndrome.

IL-5 expressed CD4+ lymphocytes Echinococcus multilocularis-infected patients.


IL-5 post-traumatic eosinophilic pleural effusion.



IL-5 induces Pgp-1 (CD44) bright B cell subpopulation highly enriched proliferative Ig secretory activity binds hyaluronate.




IL-5 predominant eosinophil-active cytokine antigen-induced pulmonary late-phase response.

IL-5 levels pain intensity correlated high dengue 3 viral loads.




IL-5 mRNA expression blood lymphocytes patients Kimura's disease parasite infection.


IL-5 priming PMA-induced oxidative metabolism human eosinophils allergic normal subjects pollen season.

IL-5 production CD4+ T cells asthmatic patients suppressed glucocorticoids immunosuppressants FK506 cyclosporin A.


IL-5 production bone marrow stromal cells - Implications eosinophilia asthma.


IL-5 production peripheral blood Th cells adult asthma patients answer Candida albicans allergen.